张卫光,男,医学博士,教授,博士研究生导师,北京市高校教学名师、教育部课程思政教学名师。1999年研究生毕业于北京医科大学,现任北京大学医学部基础医学院解剖学与组织胚胎学系常务副主任、北京大学生物医学实验教学中心副主任、《解剖学报》编辑部主任,兼任北京解剖学会副理事长,国家医考中心出题专家,全国高校青年教师讲课比赛决赛专家评委。长期从事人体解剖学的教学和科研工作,主要研究血管的临床解剖学和遗体防腐保护及虚拟现实成像。主持国家级精品课程3门,主持教育部、中华医学会、北京大学等教学改革项目15项,主编教材或专著20部,主持国家自然科学基金和北京市自然基金等的科研项目十余项,发表教学和科研论文70余篇。曾获“北京市高校教学名师”、“全国卫生系统青年岗位能手”、“北京市高校青教赛优秀指导教师”、“北京大学卓越奖”、“北京大学十佳教师”、“北京大学医学部名师”等多项表彰。
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承担科研和教学项目
主持北京市自然基金海淀前沿专项《基于三维点云的混合现实个性化骨关节手术模拟重建》(19L2053,2019-2022);
主持北京大学临床+X基金项目《基于影像的个性化虚拟现实模拟临床手术的研究》(2019-2020,BMU2018MI016);
主持教育部科技创新基金项目《基于影像的骨关节医学混合增强现实模拟及评测教学系统的研究》(2019-2021,2018A02011);
中华医学会医学教育分会医学教育研究重点课题《基于影像的个性化临床手术虚拟现实教学系统》(2018-2020,2018A-N05058);
主持中华医学会医学教育分会医学教育研究课题《构建医学生人文化的人体解剖学教育教学体系》(2016-2018);
主持北京大学“新思路”教改项目《基于影像的骨关节医学混合现实模拟及评测教学系统的研究》(2019,2019ZD003);
主持北京市自然科学基金项目《分数阶微积分研究肝血窦内非定常流动对肝细胞脂肪变性的影响》(2016-2018,7162098);
分课题主持国家自然科学基金委重大研究项目《慢性痛状态下前额叶皮层及其相关环路对痛觉信息编码的调控机制》(2016-2020,31530028);
分课题主持国家自然科学基金委重大研究计划培育项目《前额叶皮质调控痛记忆和痛负性情绪及其交互敏化的微环路及分子网络基础》(2014-2016,91332119);
分课题主持首都市民健康项目《完整结肠系膜切除术的基础与临床研究》(2012-2014,Z12110000);
参与首都发展基金重点科研专项《结肠系膜的基础与临床研究》(2011-2013);
参与国家基础科学人才培养基金项目《北京大学基础医学基地》( J1103605,2012-2015);
主持国家自然科学基金资助项目《肝门静脉高压症血液动力学的整体生物力学模型》(批准号:30170244,2002-2004);
分课题主持国家自然科学基金项目《人肝干细胞和间充质干细胞移植逆转肝硬变及人工肝的研究》(批准号:30471638,2005-2007);
主持国家基础科学培养基金及北京大学的“创新人才培养”项目子课题《内质网应激性在肝硬化形成中的作用》,2006-2008年,负责部分医学八年制创新人才培养;
分课题主持北京大学“985”跨学科研究项目《心血管动力学中两个重要课题的基础与临床研究》(批准号:Bio-x,2002-2004);
主持北京大学“985”教改项目《解剖学标本陈列室的改建》;
负责北京大学医学部教改项目《八年制解剖学教学改革》;
参与完成了国家自然科学基金项目《低功率激光影响血管重建的实验研究》(批准号:39470363);
参与了国家自然科学基金项目《成人心肌的修复与再生》(批准号:30370745)。
参与完成了国家自然科学基金项目《子宫内膜异位症人体组织学模型的构建及在位内膜异常在该病的启动机制中的作用》(批准号:30471817)。
参与完成了国家自然科学基金项目《绒癌耐药细胞株多种耐药基因逆转的研究》(批准号:30000179)。
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发表的部分教学科研论文
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Pu D, Ni J, Song D, Zhang W, Wang Y, Wu L, Wang X, Wang Y*. Influence of critical thinking disposition on the learning efficiency of problem-based learning in undergraduate medical students. BMC Medical Education, 2019,19(1):1-8.
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Yan JH, Ding XL, Qin LH, Zhang WG*. Team-based learning: assessing the impact on Anatomy teaching in China. Advances in Medical Education and Practice, 2018,9(8):589-594.
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Chen C, Zhang W*, Qin L, Cui H, Linghu D, Guan Y, Wang X, Zhou C. Problem-based learning in Gross Anatomy: Assessment Outcomes and Student Perceptions. J Biology Life Science, 2013, 4(1), 194-204.
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Wang J, Zhang W*, Qin L, Zhao J, Zhang S, Gu J, Zhou C. Problem-based learning in regional anatomy education at Peking University. Anat Sci Educ. 2010, 3(3),121-126.
5. Wang Jianwei, Cheng Quancheng, Fang Jinyu, Ding Huiru, Liu Huaicun, Fang Xuan, Chen Chunhua*, Zhang Weiguang*. Inhalation of hydrogen gas alleviates early CCl4-induced chronic liver injury in rats by upregulation of UCP2. Antioxidants,2021,10,1933(Q1,6.312)
6. Cheng Quancheng, Ding Huiru, Fang Jinyu, Fang Xuan, Liu Huaicun, Wang Jianwei, Chen Chunhua *, Zhang Weiguang*. Aquaporin 9 represents a novel target of chronic liver injury that may antagonize its progression by reducing lipotoxicity. Oxid Med Cell Longev.(accepted, IF=6.543,Q2)
7. Cheng QC, Chen X, Ma J, Jiang X, Chen J, Zhang M, Wu Y, Zhang WG*, Chen CH*. Effect of Methylene Blue on white matter injury after ischemic stroke. Oxid Med Cell Longev, 2021, 1-10.(Q2区, 6.54)
8. Liu Z, Ding H, She J, Chen Ch, Zhang W*, Yang E*. DEBKS: A tool to detect differentially expressed circular RNA. Genomics, Proteomics & Bioinformatics, 2021, 19(1), s1672-0229.(IF 7.69, Q1区)
9. Shen Y, Zhou Q, Sun X, Qiu Z, Jia Y, Li S*, Zhang W*. Safe needling depth at abdominal traditional acupuncture points: a ultrasonographic study of cadavers. Acupunct Med,2021,39(2),156-158.(2.263, Q3)
10. zhang J, Yang X, Ding HR, Zhang L, Xu YY, Sang XT, Zhao HT,Zhang WG, Lu X. Is Aspirin a Drug or Just a Marker for Biliary Cancer? Hep, 2021, 2924.
11. WangD, ShenZ, YangS, ZhangB, LiY, FangY, JiaoC, GuoQ, ZhangW*, JiangD*. A novel transverse talar tunnel achieved less vessel damage and better drilling safety for ATFL reconstruction: A cadaveric study with three-dimensional MicroCT. AJTR, 2020,12(12),8050-8058. (Q2区, 2.6).
12. Sun H, Liu C, Li X, Liu H, Zhang W(责任作者), Yang H, Li C, Yang L. A novel calcium phosphate -based nanocomposite for the augmentation of cement-injectable cannulated pedicle screws fixation: A cadaver and biomechanical study. JOT, 2020(20) ,56-66. (Q1区,5.2)
13. Cheng QC, Fan J, Deng XW, Liu HC, Ding HR, Fang X, Wang JW, Chen CH, Zhang WG*. Dihydromyricetin ameliorates chronic liver injury by reducing pyroptosis. World J Gastroenterol, 2020; 26(41): 6346-6360. (IF 5.74,Q2)
14. Liu H, Su D, Liu L, Chen L, Zhao Y, Chan S,Zhang W*, Wang Y*, Wang J*. Identification of a new functional domain of Nogo-A that promotes inflammatory pain and inhibits neurite growth through binding to NgR1. FASEB J, 2020,34(5):10948–10965.(IF 5.19,分区Q1)
15. Yang Y, Zhang W, Li Z, Chen S, Tian W. Anatomical and clinical study of a new mallet fracture classification method. Chin Med J (Engl) ,2020,133(6),657-663.(IF 1.0,分区Q2)
16. Wang DY, Shen ZC, Fang X, Jiang D*,Zhang WG*. Vascular compromising effect of drilling for osteochondral lesions of the talus: a three-Dimensional micro-computed tomographic study. Arthroscopy, 2019, 35 (10):2930-2937. (IF 4.77,分区Q1)
17. Wang DY, Shen ZC, Jiang D, Li X, Fang X, Leng HJ*, Zhang WG*. Qualitative and quantitative analysis of patellar vascular anatomy by novel 3D Micro CT: Implications for total knee arthroplasty. The Knee, 2019, 26(6), 1330-1337. (IF 1.9,分区Q2)
18. Fan J, Chen CJ, Wang YC, Quan W, Wang JW, Zhang WG*.Hemodynamic changes in hepatic sinusoids of hepatic steatosis mice. World J Gastroenterology, 2019, 25(11): 1355-1365. (IF 3.4,分区Q2)
19. Zhu X, Shen Y, Liu Z, Gu P, Li S, Zhang W. Ultrasound-guided percutaneous release procedures in the lumbar ligamentum flavum by acupotomy: A cadaveric study. Evid Based Complement Alternat Med, 2019, 23(11), 1-9.(IF 1.7,分区Q3)
20. Feng H, Wang JY, Yu B, Cong X, Zhang WG, Wu LL*. Peroxisome proliferator -activated receptor-γ coactivator-1α inhibits vascular calcification through sirtuin 3-mediated reduction of mitochondrial oxidative stress. Antioxid Redox Signal, 2019,31(1),75-91. (IF 6.7,分区Q1)
21. SunJ,YangX, ZhangY,ZhangW, LuJ, HuQ, LiuR,ZhouC, ChenC*. Salvinorin A attenuates early brain injury through PI3K/Akt pathway aftersubarachnoid hemorrhage in rat. Brain Research, 2019,1719(3): 64–70.(IF 2.2,分区Q2)
22. Xiao ZR, Xiong G*, Zhang WG. New findings about the intrascaphoid arterial system. J Hand Surg Eur, 2018, 43(10): 1059-1065. (IF 2.3,分区Q2)
23. Ma JX, Yang QM, Xia YC, Zhang WG, Nie FF. Effect of 810?nm Near-Infrared Laser on Revascularization of Ischemic Flaps in Rats. Photomed Laser Surg, 2018,36(6): 290-297. (IF 2.0,分区Q3)
24. Wang ZY, Zhang WG. Chitin biological absorbable catheters bridging sural nerve grafts transplanted into sciatic nerve defects promote nerve regeneration. CNS Neuroscience & Therapeutics, 2018,24(6):483-494. (IF 3.9,分区Q2)
25. Sun J, Zhang W, Zhou C, Chen C*. Salvinorin A ameliorates cerebral vasospasm through activation of endothelial nitric oxide synthase in a rat model of subarachnoid hemorrhage. Microcirculation, 2018, 25(3):e12442. (IF 2.4,分区Q2)
26. Xu X, Zhao S, Liu H, Sun Z, Wang J, Zhang W*. An anatomical study of maxillary -zygomatic complex using three-dimensional computerized tomography -based zygomatic implantation. BioMed Research International,2017,12(11),1-8.(IF 2.48,分区Q3)
27. Xu J, Tian X, Chen Y, Ma Y, Liu C, Tian L, Wang J, Dong J, Cui D, Wang Y,Zhang W*, Yang Y*. Total mesopancreas excision for the treatment of pancreatic head cancer. J Cancer,2017; 8(17): 3575-3584.(IF 2.9,分区Q2)
28. Xiao ZR#, Zhang WG#, Xiong G, Zhang YL. Three-dimensional intralunate arteries visualization with Red Lead (Pb3O4) angiography. Chin Med J (Engl). 2017, 130(11),2575-2578.(IF 1.0,分区Q2)
29. Xiong G, Xiao ZR, Zhang WG. Vascular anatomy of the capitate determined by micro-computed tomography angiography. J Hand Surg Eur. 2017,42(9):966-967.(IF 2.1,分区Q2)
30. Qin R, Cao S, Liu T, Qi C,Zhang W, Wang Y. CDYL deficiency disrupts neuronal migration and increases susceptibility to epilepsy. Cell Reports, 2017, 18(1):380–390.(IF 7.1,分区Q1)
31. Zheng L, Ding J, Wang J, Zhou C, Zhang W*. Effects and mechanism of action of inducible nitric oxide synthase on apoptosis in a rat model of cerebral ischemia-reperfusion injury. Anat Rec, 2016, 299(2):246-255.(IF 1.7,分区Q2)